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Jake Driftwood Spa; Jamaica South CoastCan technology and vacation vacation difficult it also. Many travellers are using Wi-Fi Hotel hook, use the work email in the beach or check their Blackberrys. Really, is only solution for off grid for some of. Charging the battery of non-distance can travel take a look at our top choice unplugged retreat — requires no batteries.
Figures and tables from this article:
Fig. 1. Representation of an integrated model of behaviour change (Adapted from Ajzen50).View Within ArticleTable 1. Downs and Black (1998)28 criteria used in the methodological quality evaluation of the reviewed studies.
All items scored 0 or 1, except “description of principal confounders”, which scored 0, 1, or 2.View Within ArticleTable 2. General characteristics of school sleep education programs.* ACES = Australian centre for education in sleep, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.View Within ArticleTable 3. Summary of measures, design and results.ACES = Australian centre for education in sleep, DST = delayed sleep timing, PSQI = Pittsburgh sleep quality index, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.View Within ArticleTable 4. Quality of studies (not including abstracts).View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.prs.rt('data_end');
Figures and tables from this article:
Fig. 1. Representation of an integrated model of behaviour change (Adapted from Ajzen50).View Within ArticleTable 1. Downs and Black (1998)28 criteria used in the methodological quality evaluation of the reviewed studies.All items scored 0 or 1, except “description of principal confounders”, which scored 0, 1, or 2.View Within ArticleTable 2. General characteristics of school sleep education programs.* ACES = Australian centre for education in sleep, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.View Within ArticleTable 3. Summary of measures, design and results.ACES = Australian centre for education in sleep, DST = delayed sleep timing, PSQI = Pittsburgh sleep quality index, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.View Within ArticleTable 4. Quality of studies (not including abstracts).View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.prs.rt('data_end');
Figures and tables from this article:
Fig. 1. Representation of an integrated model of behaviour change (Adapted from Ajzen50).View Within ArticleTable 1. Downs and Black (1998)28 criteria used in the methodological quality evaluation of the reviewed studies.All items scored 0 or 1, except “description of principal confounders”, which scored 0, 1, or 2.View Within ArticleTable 2. General characteristics of school sleep education programs.* ACES = Australian centre for education in sleep, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.View Within ArticleTable 3. Summary of measures, design and results.ACES = Australian centre for education in sleep, DST = delayed sleep timing, PSQI = Pittsburgh sleep quality index, RCT = randomised controlled trial, STEPS = sleep treatment and education program for students.View Within ArticleTable 4. Quality of studies (not including abstracts).View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.prs.rt('data_end');
Tea at the Chesterfield MayfairThere’s really nothing more English than afternoon tea, and so in honor of the Queen’s Diamond Jubilee this June, we’ve rounded up some of our favorite spots to indulge — in London and the Commonwealth.
We found scones, clotted cream, and smoked salmon finger sandwiches, of course, but a few surprises as well — from poetry tea readings to a tea inspired by the royal jewels.
Pinkies up, please!
Fig. 1. Potential interplay of pathologic factors in secondary RLS. Abbreviations: RLS: restless legs syndrome; Inflam & Immune: inflammation and/or altered immunity; SIBO: small intestinal bacterial overgrowth; Neuropathy: peripheral neuropathy.
View Within ArticleFig. 2. [26], [55], [56] and [125] of hepcidin synthesis in the setting of inflammation and theoretical consequences for developing CNS iron deficiency and subsequent RLS. Hepcidin is the main hormone involved in regulation of iron levels and has been shown to be produced by the liver in humans and in the brain in animal models. Increased hepcidin levels lead to iron deficiency. Interleukin-6 is the main cytokine that can increase hepcidin levels. Lipopolysaccharides which are breakdown products of gram negative bacteria stimulate hepcidin synthesis. Hypoxia also stimulates hepcidin synthesis. Hepcidin binds to ferroportin on human choroid plexus cells and decrease availability of iron for the CNS. Not shown – Bacteria may also utilize iron and cause iron deficiency.57 Abbreviations: LPS: lipopolysaccharides.
View Within ArticleTable 1. Iron deficiency, small intestinal bacterial overgrowth (SIBO), inflammation and/or immunological alterations and peripheral neuropathy in conditions associated with restless legs syndrome (RLS). References are categorized as either: a controlled study (CS); an observational case series (OS); a laboratory study (LS) which uses defined assays but does not have a control group; or a review article (RA). Highly-associated conditions are defined as RLS conditions shown to have a statistically higher prevalence than controls. This table does not include seven single case reports associated with RLS (see result section).
Additional abbreviations: ADHD: attention-deficit/hyperactivity disorder; COPD: chronic obstructive pulmonary disease; NS: not studied.View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.
Fig. 1. Potential interplay of pathologic factors in secondary RLS. Abbreviations: RLS: restless legs syndrome; Inflam & Immune: inflammation and/or altered immunity; SIBO: small intestinal bacterial overgrowth; Neuropathy: peripheral neuropathy.
View Within ArticleFig. 2. [26], [55], [56] and [125] of hepcidin synthesis in the setting of inflammation and theoretical consequences for developing CNS iron deficiency and subsequent RLS. Hepcidin is the main hormone involved in regulation of iron levels and has been shown to be produced by the liver in humans and in the brain in animal models. Increased hepcidin levels lead to iron deficiency. Interleukin-6 is the main cytokine that can increase hepcidin levels. Lipopolysaccharides which are breakdown products of gram negative bacteria stimulate hepcidin synthesis. Hypoxia also stimulates hepcidin synthesis. Hepcidin binds to ferroportin on human choroid plexus cells and decrease availability of iron for the CNS. Not shown – Bacteria may also utilize iron and cause iron deficiency.57 Abbreviations: LPS: lipopolysaccharides.
View Within ArticleTable 1. Iron deficiency, small intestinal bacterial overgrowth (SIBO), inflammation and/or immunological alterations and peripheral neuropathy in conditions associated with restless legs syndrome (RLS). References are categorized as either: a controlled study (CS); an observational case series (OS); a laboratory study (LS) which uses defined assays but does not have a control group; or a review article (RA). Highly-associated conditions are defined as RLS conditions shown to have a statistically higher prevalence than controls. This table does not include seven single case reports associated with RLS (see result section).
Additional abbreviations: ADHD: attention-deficit/hyperactivity disorder; COPD: chronic obstructive pulmonary disease; NS: not studied.View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.
Fig. 1. Potential interplay of pathologic factors in secondary RLS. Abbreviations: RLS: restless legs syndrome; Inflam & Immune: inflammation and/or altered immunity; SIBO: small intestinal bacterial overgrowth; Neuropathy: peripheral neuropathy.
View Within ArticleFig. 2. [26], [55], [56] and [125] of hepcidin synthesis in the setting of inflammation and theoretical consequences for developing CNS iron deficiency and subsequent RLS. Hepcidin is the main hormone involved in regulation of iron levels and has been shown to be produced by the liver in humans and in the brain in animal models. Increased hepcidin levels lead to iron deficiency. Interleukin-6 is the main cytokine that can increase hepcidin levels. Lipopolysaccharides which are breakdown products of gram negative bacteria stimulate hepcidin synthesis. Hypoxia also stimulates hepcidin synthesis. Hepcidin binds to ferroportin on human choroid plexus cells and decrease availability of iron for the CNS. Not shown – Bacteria may also utilize iron and cause iron deficiency.57 Abbreviations: LPS: lipopolysaccharides.
View Within ArticleTable 1. Iron deficiency, small intestinal bacterial overgrowth (SIBO), inflammation and/or immunological alterations and peripheral neuropathy in conditions associated with restless legs syndrome (RLS). References are categorized as either: a controlled study (CS); an observational case series (OS); a laboratory study (LS) which uses defined assays but does not have a control group; or a review article (RA). Highly-associated conditions are defined as RLS conditions shown to have a statistically higher prevalence than controls. This table does not include seven single case reports associated with RLS (see result section).
Additional abbreviations: ADHD: attention-deficit/hyperactivity disorder; COPD: chronic obstructive pulmonary disease; NS: not studied.View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.
By Rachel Felder
Gearing up for a summer getaway is certainly exciting; figuring out what's appropriate to wear on your trip, well, not so much. Whether you're heading to a vibrant European capital or an ultra-relaxing beach resort, knowing what to pack can be a daunting task. For men, the safest plan, regardless of destination, is to keep things simple, packing versatile basics in neutral shades of navy, gray, khaki, black, and white.
"I would definitely bring an unlined blazer that's comfortable and more casual but still gives you the look of a tailored jacket," suggests Matt Marden, Fashion Market Director at DETAILS magazine. "Something like a navy suit or a gray suit is also great to bring because you can break up the pieces and dress them up or down with a white button down or a navy blue t-shirt."
Marden also suggests bringing jeans in dark denim (since it's more polished than lighter washes), a pair of comfortable dress shoes, and a pair of classic white sneakers, which can be worn with a suit (to give it a more casual feel) as well as shorts and a simple tee.
Of course, some of what needs to be packed depends on where you're going. Here are Marden's tips for the most popular types of summer destinations:
"If you're going to be in a city in the summer, it's great to get key items in fabrics like cotton and linen," Marden advises. "They have an effortless feel to them and look chic even if they get wrinkly." What not to pack? "I would not bring anything like a flip-flop, any sort of gym shorts unless you're going to run in them, or graphic t-shirts or destination t-shirts. Most quote unquote 'tacky tourists' wear a lot of logos, so I would avoid logos at all costs, even on your luggage."
For this type of trip, the goal is to look relaxed and lowkey "I love wearing a pair of shorts—more of a tailored short, nothing 'cargoey' with tons of pockets—with a dress shoe if you're going to a small town," Marden says "Another great thing is bringing a grey sweatshirt, because that looks good with khakis and it's super comfortable, easy, and breathable if you're running all around. If you're sightseeing in the morning and it's cool you can wear it, then wrap it around your waist or shoulders as it gets warmer later in the day."
"Unless you're a male model or an Olympian—or have the body of either—you don't want to be rocking a Speedo on the beach," Marden laughs, suggesting that swim trunks should fall between mid-thigh and just above the knee. "Grown men should not be wearing any sort of board shorts because that gets to be a little goofy."
For the journey to and from your destination, Marden says the priority is ease. "I love a chino on the airplane, or a dress pant, because they're comfortable," he says. "Jeans get to be too heavy sometimes. A slim fitting cargo pant also would work." He also suggests wearing a cardigan sweater, since planes can get drafty.
For up-to-the-minute hotel and restaurant recommendations, as well as the best planning advice, check out our Europe Travel Guide.
But although it's important to be comfortable, particularly for long haul flights, Marden says not to take that goal too far. "I would never wear sweatpants," he says.
Photo Credits: Chic European City: TommL/iStockphoto.com; Small Town:
, 
, Jan Ulfbergb, Klaus Bergerc, Imad Ghorayebd, Jan Wesströme, Stephany Fuldaf, Richard P. Alleng, Thomas Pollmächerf, ha Sleep and Epilepsy Center, Neurocenter (EOC) of Southern Switzerland, Civic Hospital, Lugano, Via Tesserete 46, 6900 Lugano, Switzerlandb Department of Medicine, Uppsala University, Uppsala, Swedenc Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germanyd Clinical Neurophysiology Department, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux cedex, Francee Center for Clinical Research Dalarna, Department of Women's and Children's Health, Uppsala University, Swedenf Max Planck Institute of Psychiatry, Munich, Germanyg Center of Mental Health, Klinikum Ingolstadt, Ingolstadt, Germanyh Department of Neurology, Johns Hopkins University, Bayview Medical Center, Baltimore, MD, USAReceived 13 May 2011. Revised 30 August 2011. Accepted 30 August 2011. Available online 9 November 2011.View full text Sleep is an essential human behavior that shows prominent gender differences. Disturbed sleep, in particular, is much more prevalent in females than males. Restless legs syndrome (RLS) as one cause of disturbed sleep was observed to be somewhat more common among women than men in Ekbom's 1945 seminal series of clinical cases with the disease. He, however, reported this gender difference mainly for those with more severe symptoms. Since then numerous studies have reported that women are affected by RLS about twice as often as males for mild as well as moderate to severe RLS. The present review focuses on RLS in females from the perspectives of both epidemiology and pathophysiology. RLS will generally become worse or might appear for the first time during pregnancy. Parity increases the risk of RLS later in life suggesting that pregnancy is a specific behavioral risk factor for developing RLS. Some evidence suggests that dysfunction in iron metabolism and high estrogen levels might contribute to RLS during pregnancy. But, menopause does not lower the incidence of RLS nor does hormone replacement therapy lead to an increase, suggesting a quite complex uncertain role of hormones in the pathophysiology of RLS. Therefore, further, preferably longitudinal studies are needed to unravel the factors causing RLS in women. These studies should include genetic, clinical and polysomnographic variables, as well as hormonal measures and variables assessing iron metabolism.prs.rt("abs_end");Restless legs syndrome; Gender; Female; Sleep; Insomnia; Pregnancy; Estrogens; Menopause; Quality of lifeFigures and tables from this article:
Fig. 1. Epidemiological results on RLS and pregnancy. Histograms show the prevalence trend of RLS in a group of 606 women surveyed at the end of pregnancy. In the period before pregnancy, 60 women already experienced RLS symptoms in their life (in a non pregnancy period) and were classified as “pre-existing RLS”. The remaining 546 women had never experienced RLS symptoms before and were classified as “healthy”. During the first assessed pregnancy (2nd histogram) 101 women, out of the 546 “healthy” ones, developed a transient RLS form strictly related to the pregnancy and were classified as “pregnancy-related RLS”. All these 101 women with a new form of pregnancy-related RLS form, except 6 women, recovered after delivery (3rd histogram). Fifty nine of the same pregnancy-related RLS group suffered again RLS symptoms during a further following pregnancy. After a mean follow up of 7 years, 25 out of the 101 women who experienced the symptoms during the first pregnancy (pregnancy-related RLS group) developed a chronic apparently idiopathic RLS form even out of pregnancy. Elaborated data from the study of Cesnik et al.37View Within ArticleFig. 2. Prevalence of RLS among women in two age groups and according to number of children born in the German general practioner study.43View Within ArticleFig. 3. Median serum ferritin by age for major USA gender and population groups.View Within ArticleFig. 4. Prevalence of clinically significant RLS by gender and age from large European and United States population-based samples. (Slightly modified from Allen et al).21View Within ArticleTable 1. Studies on the prevalence of RLS performed in random samples of the general population of different countries, using the IRLSSG criteria to assess the diagnosis.View Within ArticleTable 2. Epidemiological studies published in literature on RLS prevalence that included an assessment on the quality of life.Abbreviations: EQ-5D VAS, visual analogue scale score for the EQ-5D, a quality of life questionnaire developed by the EuroQoL Group; HRQoL, health related quality of life; MCS, mental component score of the SF-36; RLS, restless legs syndrome; PCS, physical component score of the SF-36; SF-36, SF-12, short form health survey.View Within ArticleTable 3. Studies exploring the role of estrogens in RLS.Abbreviations: AC, active controlled; CO, crossover; DB, double blind; HRT, hormone replacement therapy; IQR, interquartile range; PC, placebo controlled; PG, parallel group; PLM, periodic leg movements; R, randomized; SD, standard deviation.View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.prs.rt('data_end');
, , Jan Ulfbergb, Klaus Bergerc, Imad Ghorayebd, Jan Wesströme, Stephany Fuldaf, Richard P. Alleng, Thomas Pollmächerf, ha Sleep and Epilepsy Center, Neurocenter (EOC) of Southern Switzerland, Civic Hospital, Lugano, Via Tesserete 46, 6900 Lugano, Switzerlandb Department of Medicine, Uppsala University, Uppsala, Swedenc Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germanyd Clinical Neurophysiology Department, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux cedex, Francee Center for Clinical Research Dalarna, Department of Women's and Children's Health, Uppsala University, Swedenf Max Planck Institute of Psychiatry, Munich, Germanyg Center of Mental Health, Klinikum Ingolstadt, Ingolstadt, Germanyh Department of Neurology, Johns Hopkins University, Bayview Medical Center, Baltimore, MD, USAReceived 13 May 2011. Revised 30 August 2011. Accepted 30 August 2011. Available online 9 November 2011.View full text Sleep is an essential human behavior that shows prominent gender differences. Disturbed sleep, in particular, is much more prevalent in females than males. Restless legs syndrome (RLS) as one cause of disturbed sleep was observed to be somewhat more common among women than men in Ekbom's 1945 seminal series of clinical cases with the disease. He, however, reported this gender difference mainly for those with more severe symptoms. Since then numerous studies have reported that women are affected by RLS about twice as often as males for mild as well as moderate to severe RLS. The present review focuses on RLS in females from the perspectives of both epidemiology and pathophysiology. RLS will generally become worse or might appear for the first time during pregnancy. Parity increases the risk of RLS later in life suggesting that pregnancy is a specific behavioral risk factor for developing RLS. Some evidence suggests that dysfunction in iron metabolism and high estrogen levels might contribute to RLS during pregnancy. But, menopause does not lower the incidence of RLS nor does hormone replacement therapy lead to an increase, suggesting a quite complex uncertain role of hormones in the pathophysiology of RLS. Therefore, further, preferably longitudinal studies are needed to unravel the factors causing RLS in women. These studies should include genetic, clinical and polysomnographic variables, as well as hormonal measures and variables assessing iron metabolism.prs.rt("abs_end");Restless legs syndrome; Gender; Female; Sleep; Insomnia; Pregnancy; Estrogens; Menopause; Quality of lifeFigures and tables from this article:
Fig. 1. Epidemiological results on RLS and pregnancy. Histograms show the prevalence trend of RLS in a group of 606 women surveyed at the end of pregnancy. In the period before pregnancy, 60 women already experienced RLS symptoms in their life (in a non pregnancy period) and were classified as “pre-existing RLS”. The remaining 546 women had never experienced RLS symptoms before and were classified as “healthy”. During the first assessed pregnancy (2nd histogram) 101 women, out of the 546 “healthy” ones, developed a transient RLS form strictly related to the pregnancy and were classified as “pregnancy-related RLS”. All these 101 women with a new form of pregnancy-related RLS form, except 6 women, recovered after delivery (3rd histogram). Fifty nine of the same pregnancy-related RLS group suffered again RLS symptoms during a further following pregnancy. After a mean follow up of 7 years, 25 out of the 101 women who experienced the symptoms during the first pregnancy (pregnancy-related RLS group) developed a chronic apparently idiopathic RLS form even out of pregnancy. Elaborated data from the study of Cesnik et al.37View Within ArticleFig. 2. Prevalence of RLS among women in two age groups and according to number of children born in the German general practioner study.43View Within ArticleFig. 3. Median serum ferritin by age for major USA gender and population groups.View Within ArticleFig. 4. Prevalence of clinically significant RLS by gender and age from large European and United States population-based samples. (Slightly modified from Allen et al).21View Within ArticleTable 1. Studies on the prevalence of RLS performed in random samples of the general population of different countries, using the IRLSSG criteria to assess the diagnosis.View Within ArticleTable 2. Epidemiological studies published in literature on RLS prevalence that included an assessment on the quality of life.Abbreviations: EQ-5D VAS, visual analogue scale score for the EQ-5D, a quality of life questionnaire developed by the EuroQoL Group; HRQoL, health related quality of life; MCS, mental component score of the SF-36; RLS, restless legs syndrome; PCS, physical component score of the SF-36; SF-36, SF-12, short form health survey.View Within ArticleTable 3. Studies exploring the role of estrogens in RLS.Abbreviations: AC, active controlled; CO, crossover; DB, double blind; HRT, hormone replacement therapy; IQR, interquartile range; PC, placebo controlled; PG, parallel group; PLM, periodic leg movements; R, randomized; SD, standard deviation.View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.prs.rt('data_end');
, , Jan Ulfbergb, Klaus Bergerc, Imad Ghorayebd, Jan Wesströme, Stephany Fuldaf, Richard P. Alleng, Thomas Pollmächerf, ha Sleep and Epilepsy Center, Neurocenter (EOC) of Southern Switzerland, Civic Hospital, Lugano, Via Tesserete 46, 6900 Lugano, Switzerlandb Department of Medicine, Uppsala University, Uppsala, Swedenc Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germanyd Clinical Neurophysiology Department, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux cedex, Francee Center for Clinical Research Dalarna, Department of Women's and Children's Health, Uppsala University, Swedenf Max Planck Institute of Psychiatry, Munich, Germanyg Center of Mental Health, Klinikum Ingolstadt, Ingolstadt, Germanyh Department of Neurology, Johns Hopkins University, Bayview Medical Center, Baltimore, MD, USAReceived 13 May 2011. Revised 30 August 2011. Accepted 30 August 2011. Available online 9 November 2011.View full text Sleep is an essential human behavior that shows prominent gender differences. Disturbed sleep, in particular, is much more prevalent in females than males. Restless legs syndrome (RLS) as one cause of disturbed sleep was observed to be somewhat more common among women than men in Ekbom's 1945 seminal series of clinical cases with the disease. He, however, reported this gender difference mainly for those with more severe symptoms. Since then numerous studies have reported that women are affected by RLS about twice as often as males for mild as well as moderate to severe RLS. The present review focuses on RLS in females from the perspectives of both epidemiology and pathophysiology. RLS will generally become worse or might appear for the first time during pregnancy. Parity increases the risk of RLS later in life suggesting that pregnancy is a specific behavioral risk factor for developing RLS. Some evidence suggests that dysfunction in iron metabolism and high estrogen levels might contribute to RLS during pregnancy. But, menopause does not lower the incidence of RLS nor does hormone replacement therapy lead to an increase, suggesting a quite complex uncertain role of hormones in the pathophysiology of RLS. Therefore, further, preferably longitudinal studies are needed to unravel the factors causing RLS in women. These studies should include genetic, clinical and polysomnographic variables, as well as hormonal measures and variables assessing iron metabolism.prs.rt("abs_end");Restless legs syndrome; Gender; Female; Sleep; Insomnia; Pregnancy; Estrogens; Menopause; Quality of lifeFigures and tables from this article:
Fig. 1. Epidemiological results on RLS and pregnancy. Histograms show the prevalence trend of RLS in a group of 606 women surveyed at the end of pregnancy. In the period before pregnancy, 60 women already experienced RLS symptoms in their life (in a non pregnancy period) and were classified as “pre-existing RLS”. The remaining 546 women had never experienced RLS symptoms before and were classified as “healthy”. During the first assessed pregnancy (2nd histogram) 101 women, out of the 546 “healthy” ones, developed a transient RLS form strictly related to the pregnancy and were classified as “pregnancy-related RLS”. All these 101 women with a new form of pregnancy-related RLS form, except 6 women, recovered after delivery (3rd histogram). Fifty nine of the same pregnancy-related RLS group suffered again RLS symptoms during a further following pregnancy. After a mean follow up of 7 years, 25 out of the 101 women who experienced the symptoms during the first pregnancy (pregnancy-related RLS group) developed a chronic apparently idiopathic RLS form even out of pregnancy. Elaborated data from the study of Cesnik et al.37View Within ArticleFig. 2. Prevalence of RLS among women in two age groups and according to number of children born in the German general practioner study.43View Within ArticleFig. 3. Median serum ferritin by age for major USA gender and population groups.View Within ArticleFig. 4. Prevalence of clinically significant RLS by gender and age from large European and United States population-based samples. (Slightly modified from Allen et al).21View Within ArticleTable 1. Studies on the prevalence of RLS performed in random samples of the general population of different countries, using the IRLSSG criteria to assess the diagnosis.View Within ArticleTable 2. Epidemiological studies published in literature on RLS prevalence that included an assessment on the quality of life.Abbreviations: EQ-5D VAS, visual analogue scale score for the EQ-5D, a quality of life questionnaire developed by the EuroQoL Group; HRQoL, health related quality of life; MCS, mental component score of the SF-36; RLS, restless legs syndrome; PCS, physical component score of the SF-36; SF-36, SF-12, short form health survey.View Within ArticleTable 3. Studies exploring the role of estrogens in RLS.Abbreviations: AC, active controlled; CO, crossover; DB, double blind; HRT, hormone replacement therapy; IQR, interquartile range; PC, placebo controlled; PG, parallel group; PLM, periodic leg movements; R, randomized; SD, standard deviation.View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.prs.rt('data_end');
Jimmy Im
Visiting a pub in Dublin is a classic must-do, though we can't say it's really worth dining in one. Great pub food can be had, but visitors should take advantage of the many restaurants in town offering fine dining, terrific wine lists, and locally-sourced ingredients from sprawling farmlands instead.
The food culture in Ireland is as important as a cold Guinness, reflected by several regions that host annual food festivals celebrating local, artisanal flavors and ingredients. In fact, Dublin's ever-popular Taste of Dublin will take place this June with Jamie Olivier headlining the event. The festival will showcase recently opened favorites like the Green Hen and 777, as well as Michelin-starred favorites like Bon Appetit Restaurant & Brasserie. But you don't have to wait until June to sample the city's top plates. Try one of these buzz-worthy restos anytime—at least while they're still hot.
Throw all your impressions of a typical cellar out the window. This wonderful, lower-level restaurant at the five-star, historic Merrion Hotel flaunts vaulted ceilings and elegant furnishings within an intimate, classic setting. Accolades include 'Best Hotel Restaurant in Dublin' by Food & Wine magazine, thanks to highly touted executive chef Ed Cooney who uses fresh, Irish ingredients for contemporary Irish cuisine (expect an upgraded take on traditional fish n' chips—with minted mushy peas to boot). The restaurant continues this year with its partnership with The Gloss (The Irish Times supplement) on popular six course/wines-themed dinners.
Don't Miss: The pan-roasted monkfish with lemon couscous and baby squid, Merrion chorizo, and Sun-dried tomato vinaigrette.
The Cellar Restaurant at Merrion Hotel, Upper Merrion Street, Dublin. Tel: 353 1 603 0600
Sure enough, you'll take a flight of winding stairs to enter this local haunt that's been serving up contemporary Irish fare since it was transformed from a popular bookshop and cafe six years ago. It's hard not to like the restaurant's understated, simple character with a chalkboard menu, corner bookcases, and downtown atmosphere. The cramped eatery looks over the Ha-penny Bridge (try to book one of the few tables by one of the windows) and is as buzzing as its trend-setting diners. Expect organic veggies, a variety of meats, extensive wine list, and charming wait-staff.
Don't Miss: Nicholson's hand-smoked haddock, poached in milk with onions and white Cheddar mash.
The Winding Stair 40, Ormond Quay, Dublin 1. Tel: 353 1 8727320
Don't pay mind to the unimaginative storefront and hokey green-bulb wall lights: The Farm's strong suit is obviously in the kitchen. As you would imagine with a name like the Farm, the family-owned restaurant uses locally sourced ingredients from certified Irish producers and organic and/or free range as much as possible. They work welcomed culinary magic on traditional Irish bites—from beef stew to soda bread. While the menu is meat heavy, plenty inventive vegetarian options are offered, like the wild mushroom and organic St. Tola goat cheese risotto and Sweet potato, butternut squash and spinach curry.
Don't Miss: The farm burger—organic 8 oz. beef burger with O' Neill's dry cured smoked bacon, mature smoked Gubeen cheese, sliced cornichons, and home-made relish.
The Farm, 3 Dawson Street, City Centre South, Dublin. Tel: 353 1 6718654
This scene-y French bistro on popular Trinity Street has been racking up accolades (and a cult following) since it opened two years ago. Chef Nick Munier (a regular on Hell's Kitchen) and co-owner Stephen Gibson teamed up to create a boutique menu with creative dishes that give a nod to modern French cuisine. Reservations for both lunch and dinner are recommended in this not-stuffy addition to the lively Trinity Street that's fast becoming a staple on the food scene.
Don't Miss: Start your meal with a signature glass of passion fruit Prosecco, then dive into the suckling pig belly, pithivier, roast root vegetables and whole grain mustard.
Pichet Restaurant, 14/15 Trinity Street, Dublin 2. Tel: 353 1 6771060
And then there's Chapter One, inarguably one of Dublin's most recognized institutions that is booked for special occasions and by foodies who like their fare to come with a Michelin star. One of the most awarded restaurants in Dublin, Chapter One sits in the Dublin Writers Museum (hence the play on name) and offers a chef's table (launched in 2009 with a massive renovation) and private dining in brightly lit, contemporary interiors. Thank Chef Ross Lewis for inventiveness and exciting dishes like ravioli with 36-month parmesan. The chef's love of art inspired Project Art last fall, promoting works of local artists in the restaurant.
Don't Miss: Stuffed loin of rabbit wrapped in pancetta with broad beans a la francaise, dauphine potatoes, and rabbit liver parfait. Opt for the four-course dinner menu at $86.
Chapter One, 18-19 Parnell Sq., Northside, Dublin. Tel: 353 1 8732266
For up-to-the-minute hotel and restaurant recommendations, as well as the best planning advice, check out our Dublin Travel Guide.
Jimmy Im is a freelance travel writer based in NYC. He's appeared as a travel expert on shows on the Travel Channel and LOGO and teaches travel writing courses.
Photo Credits: The Cellar Restaurant at Merrion Hotel: Courtesy of the Merrion Hotel; Winding Stair: Courtesy of The Winding Stair Restaurant; The Farm: Taste of Ireland
